Saffron, believed to have been cultivated for over 3,000 years in the Greater Khorasan region, which includes parts of modern-day Afghanistan & Iran, was a luxury item in ancient Greece and Rome, used in perfumes, cosmetics, and as a dye. Its medicinal properties were well-documented, with ancient civilizations using it to treat various ailments. Culturally significant, saffron has been integral to Persian celebrations and traditional dishes, symbolizing joy and prosperity. Moreover, it played a crucial role in historical trade routes like the Silk Road.